Tuesday, February 14, 2023

NO CHIPS ON THESE SHOULDERS


                              

Incidence of OCD - Osteochondritis Dissecans of the Shoulder In The Mudi


It’s nice to be able to write something positive about the health of the Mudi breed for a change, and the incidence of OCD (Osteochondritis Dissecans) is something we can all be happy about.

What is OCD? 
OCD is an inflammatory condition that occurs in joints, most commonly the shoulder, but it can also happen in elbows, hips and knees.

Basically, OCD is a condition in which too fast bone growth in young, growing dogs, results in painful lesions appearing in the joints, with the end result being osteoarthritis (degenerative joint disease).  OCD typically occurs between 4 – 10 months of age and is visible on x-rays. Affected dogs will limp and the joint can be swollen, painful and warm to the touch.

OCD affects males more than females, at a ratio of 2 to 1.  Both shoulder joints are usually affected, however one side is often worse than the other.  

OCD of the shoulder and elbow primarily occurs in large and giant breeds, but smaller breeds can occasionally be affected. Medium sized breeds can also be affected, as is the case with the Border Collie which has a higher than expected incidence of OCD for many years.  

The causes are not fully known, but heredity, fast growth, improper diet (high protein, high fat, excess calcium) and hard surfaces have all been linked with OCD occurrence.

Is OCD Shoulder Dysplasia?
OCD is one of several diseases that affect the shoulder. Shoulder Dysplasia (SD) is a separate disease.  SD usually affects small and medium sized breeds and is characterized by laxity of the shoulder joint, fortunately SD is not very common.

Shoulder synovial osteochondromatosis/synovial chondrometaplasia is a rare disease that also affects larger dog breeds and has a different presentation than OCD or SA, with age of onset being 1 to 11 years of age.

There are several other shoulder diseases, but these also have different age of onset, causes and symptoms, and are also rather uncommon.

For more information on OCD and other shoulder diseases, there are some links to reliable sources at the bottom of this post.

OCD Statistics for the Mudi
Shoulders are not commonly checked during orthopedic exams made on a Mudi, however 81 owners have performed OCD screening between 2004 and 2021. 

 


The OCD screening results are given as free/clear/unaffected/not visible (FCI) or normal (OFA) for dogs that do not have indications of OCD.  If the dog has signs of OCD, the test results indicate OCD was found/visible and more specific details are sometimes given.

Of these 81 OCD exams, 29 are confirmed official results, that is, I have seen the results either on an official website or on documents shared with me by the owner or breeder.  The other 52 OCD results mainly came from FB advertisements on which owners wrote that the OCD test was done on one or both parents of a litter or on a stud being promoted.  Whether or not the OCD exams were truly done, is not a sure thing, but it is likely that they were examined as anyone interested in a puppy or the stud could ask for the written test results to be shown to them.  

OCD screening was done by Mudi owners in 13 countries.  
 

OCD testing was done on 40 males and 41 females and the results were all free/clear/normal/unaffected – none of the 81 Mudis was reported to have OCD.  

Should I check my Mudi for OCD?
If you can afford to check for OCD, by all means please do.  However if you have limited funds that cannot pay for every possible orthopedic exam, please be sure to perform the most important orthopedic exams: hips, elbows, patellas and spine.

While no known case of OCD has occurred in the Mudi, as far as I know, it is not impossible for OCD to appear.  However by continuing to check and reporting all results, we will be much better prepared to deal with OCD occurrence. 

If your Mudi has been screened for OCD, please send the exam results to me through FB Messenger or email: MudiDirections at gmail.com


Links and References:












Wednesday, January 18, 2023

More Faces of Epilepsy, 2023 Edition

 


(Ez a cikk magyarul megtalálható ezen a blogon - Az epilepszia újabb arcai


My responsibility to the Mudi is not something I take lightly, what is best or important for the breed must always come first.  I hope that everyone involved in the Mudi breed also feels this same way and will do whatever has to be done when it comes to the best interests of the breed, however hard it may be, whether you are a breeder or an owner.

Since my last post about the incidence of epilepsy in September 2020, 17 more cases of epilepsy have appeared, that’s a 33% increase in just 2 years (please click on the purple Mudi Epilepsy Awareness ribbon on the right side of this blog to read that article in English and Hungarian). 


Kora’s Destiny

I was contacted recently by an owner whose Mudi Kora had epilepsy.  They shared with me information about their Mudi, videos of her seizures, which are placed below, as well as the progression of the seizures and the final outcome for their Mudi girl.

Kora was sent to this owner from another owner who no longer wanted her, at 6 months of age.  Very soon after she arrived, she started to have full body/generalized (also known as grand mal) seizures.  She continued to have more seizures and have them more frequently.  She was on anti-seizure medication and also CBD oil, neither of which helped.  The seizures started to come daily until she had a seizure that would be her last, as it could not be stopped, and Kora’s life ended, at only 19 months of age, from idiopathic epilepsy.

Kora’s seizures started at a very young age, before she could had puppies of her own, but that is not always the case.  While most seizures from idiopathic epilepsy occur before 4 years of age, today many Mudis are being bred that have not even reached the age of 2.  This is incredibly irresponsible in a breed that is known to have epilepsy and every Mudi breeder is aware that epilepsy does occur, it has not been kept in deep secrecy since 2008. There is no justifiable reason to breed any Mudi before it reaches the age of two.


Relative Chaos

Kora’s father has produced at least 4 litters/18 puppies, born in 2019 and 2020 and is still available for breeding.  One of his puppies has already been bred twice, with 16 puppies being born, and will have a 3rd litter in 2023. Besides Kora, he has another puppy that had a seizure in the spring of 2022. At least 6 puppies/grand-puppies have been exported to other countries.

Kora’s mother has at least 5 litters with 22 puppies already born, in 2018, 2019, 2020, 2021 and 2022, with a 6th litter planned for 2023.  Four of her pups have already been bred at least 6 times, which produced 31 puppies.  At least 8 of these puppies have been exported from their country of birth and 2 of them have produced at least 17 puppies in their new country.

Additionally, Kora’s grandparents were also widely bred, with puppies placed in many countries around the world and 2 grandparents are still available for further breeding.

As for the other 3 Mudis in the photo montage above, they have not been bred either, but their parents have produced at least 72 puppies, with many being exported from their country of origin and used in breeding.  Littermates have also reproduced.

Considering the above reproduction rate from typical Mudi parents, it’s easy to see how epilepsy genes can be spread far and fast, around the world and the gene pool. 

The most important reason for informing Mudi breeders and owners about epileptics in the breed, is the need for knowing the family connection between the affected Mudi, their parents, littermates and offspring, to other Mudis living in many parts of the world.  Knowing where epilepsy occurs can help to prevent it from occurring again, by not breeding any direct relatives and not breeding any mates together that are considered high risk.


Minimal Statistics

Besides Kora, 16 more cases of epilepsy have been brought to my attention since September 2020.  Seven are confirmed and ten are highly suspected to have idiopathic epilepsy (IE).  There have also been 2 cases of paroxysmal dyskinesia (PD) which is either another form of epileptic seizure (such as focal and generalized) or a related neurological disorder.  The University of Minnesota is studying PD and they currently consider PD to be another form of IE seizure presentation.

Current Epilepsy Statistics as of January 2023 
(figures do not include 2 PD cases)

Total Epilepsy Cases:  73 (55 in 2020)

Confirmed: 46 (39 in 2020)

Highly Suspected: 27 (16 in 2020)

What has also changed since 2020 is the rate at which Mudis, particularly those used in breeding, are connected to more than just one epileptic, further indicating the epilepsy seen in the Mudi is genetic.  Also the incidence of PD is on pedigrees that also have considerable occurrence of epilepsy, indicating it is most likely not a separate disease, but another presentation form of seizure.

What is really concerning is how many epileptic Mudis we don’t know about, making these statistics above the bare minimum. 


Damage Control

We can continue to look the other way and ignore what is right in front of us and denied by many breeders still, and I can continue to record the cases of epilepsy and write new articles that show exponential occurrences, or every breeder can finally decide to follow the breeding strategy goals I covered in my seminars that will help to reduce the occurrence of epilepsy. You can be the cure, or you can be the cause, the choice is yours, but time is running out.  Time certainly was against these 4 Mudis, for 2 of them, time stopped completely.

Having a Mudi affected with epilepsy is hard enough, please don’t make it harder for these owners by contacting them or sharing their names.  If you have questions, please ask ME.

I asked for permission from each of these owners to use the name of their Mudi and provide a picture for this article, as well as permission to use the videos they sent me.

If you have a Mudi that is having seizures, you are welcome to share your Mudis information with me.  Information that would divulge the identity of the Mudi or owner is never shared without permission.  The information about your Mudis seizures helps me to help breeders produce litters with lower risk for epilepsy occurrence.  This is vitally important to the future of the Mudi breed and those who want a Mudi to share their life with.

For more information, to report epilepsy, or any health issue that has occurred in your Mudi, please email, in any language: MudiDirections at gmail.com


Meet the Fated Four

The 4 Mudis in the photo montage at the beginning of this post are:

1) ‘Kora’

Born: July, 2020, black female (COI: 4.1%)

Kora died in February 2022, during a seizure event at 19 months of age.  She started to have seizures at 6 months of age, which increased over time and were not able to be controlled with medication.

Warning! These videos may be disturbing to some viewers!

 

Kora 1



Kora 2



2) ‘Pásztor’

Born: August, 2019, black male (COI: 0%)

Pásztor is currently doing well on medication which keeps him mostly seizure free. He started to have seizures at 1 ½ years of age.

Warning! These videos may be disturbing to some viewers!

 

Pásztor 1



Pásztor 2



3) ‘Cifra’

Born: May, 2018, black merle female (COI: 5.4%)

Cifra is currently doing well on medication which keeps her mostly seizure free. Her first seizure appeared at 3 ½ years of age.

 

4) ‘Bögöly’

Born: October, 2014, black female (COI: 10.3%)

Bögöly died in 2022 during a seizure event at 8 years of age, she had seizures from at least 4 years of age when she was rehomed with her final owner. It is quite likely they started before 4 years of age, but it was not disclosed to her final owner by the previous owners.


Positive Fate

I wish I could say the future looked bright for the Mudi breed.  But with 90+ diseases being tracked that have occurred over these last two decades, and with several serious health issues occurring at disturbing rates, it’s just not possible to be positive about the Mudi breeds future.  I can’t change this bleak destiny alone, however we can all work together to change the grim fate that lies ahead to a better outcome.

I hope you will change your course to the healthier path forward for the Mudi breed, rather than remaining on the dead-end street it currently travels.  Make this a New Year’s resolution you will fulfill!